supplement

Berberine

A targeted, plant-derived botanical to support your metabolic balance and structured routine.

Metabolic Balance

€32,00 EUR

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Quantity

Free shipping from 39€
Delivery 48–72 h · Iberian Peninsula
Easy returns within 30 days

Composition

What's in every capsule

485 mg per capsule
A single standardised capsule — the amount is declared, not approximated.
97% berberine, HPLC-verified
Measured by laboratory assay (HPLC), so the figure on the label is the figure in the capsule.

About the formula

Berberis aristata root bark. Standardised to 97% berberine (HPLC).

Berberine is an alkaloid found in the root bark of Berberis aristata, a shrub native to the Himalayas. Welleo uses a standardised dry extract at 97% berberine, measured by laboratory assay (HPLC).

Each capsule contains 485 mg of extract. The full composition and the recommended intake are declared below. Read them, and speak to your doctor or pharmacist before you start.

Key ingredients

Meet the ingredients

Berberine
485 mg (1 cap) / 1,455 mg (3 caps)
An alkaloid from the root bark of Berberis aristata, standardised to 97%.

Source

Berberis aristata root bark — Himalayan shrub

Form

Standardised dry root bark extract, 97% berberine (HPLC)

Origin

India / Himalayas

Nutrient	Per serving	% NRV
Barberry root bark dry extract (97% berberine)	500 mg / 1,500 mg	-
Of which: Berberine	485 mg / 1,455 mg	-

NRV = Nutrient Reference Value.

How to Take It

Daily dose
1 capsule per day, providing 485 mg of Berberis aristata root bark extract (97% berberine). Start at 1 capsule and do not increase without professional advice.
When to take it
15 to 30 minutes before your main meal.
How to take it
With half a glass of water (about 125 ml).
Before you start
Speak to your doctor or pharmacist before taking this product, in particular if you take any prescription medication.

Formula quality

Why choose this supplement?

Root bark, not whole plant
Extracted from the root bark of Berberis aristata only.
Standardised to 97%
The berberine content is set by specification and measured by laboratory assay (HPLC).
Clean Formulation
Packed in a transparent capsule with zero artificial colors, synthetic dyes, or titanium dioxide.

Transparency

Questions before you start

What is berberine, and where does ours come from?

Berberine is an alkaloid that occurs naturally in several plants. Ours is extracted from the root bark of Berberis aristata, a shrub from the Himalayas, and standardised to 97% berberine, measured by laboratory assay (HPLC). Each capsule contains 485 mg of that extract.

When should I take it?

Our label recommends taking it 15 to 30 minutes before your main meal, which is the intake pattern used in the published literature on this ingredient. If your doctor or pharmacist advises something different, follow their advice rather than ours.

Are there any safety limits or contraindications?

Yes, and they matter. Do not take this product if you are pregnant or breastfeeding, and do not give it to children or adolescents. It is not recommended if you have diabetes, low blood pressure, or a liver or heart condition. Berberine may lower blood sugar and blood pressure and interacts with many prescription medicines, including those for diabetes and blood pressure, immunosuppressants, and medicines processed by the liver — speak to your doctor or pharmacist before you start. Stop taking it and seek medical advice if you notice yellowing of the skin or eyes, dark urine, or persistent abdominal pain.

What does HPLC mean?

HPLC stands for high-performance liquid chromatography. It is a standard laboratory method for measuring exactly how much of a given compound is in a sample: the material is dissolved and pushed through a column that separates its components, and a detector measures each one as it comes out. When a page here says an extract is standardised to a certain percentage (HPLC), that is the method behind the number — the concentration is measured in a lab, not estimated from the plant.

Is berberine under review in Europe?

Yes. EFSA published a draft opinion on berberine in January 2026 and was not able to establish a safe intake level; the final opinion is expected in early 2027, after which the European Commission will decide whether to restrict it. Rules already differ by country — Belgium, for example, sets a much lower maximum than Spain. We are following the process and will update this page as it develops.

With a test

Know your baseline

Testing tells you where you are before you change anything. Tests are available at pharmacies and healthcare providers — get a baseline, then talk it through with them.

Baseline first
Measure your current levels at a pharmacy or your doctor before supplementing.
Smarter dosing
Align intake with real markers, not guesswork.
Track progress
Retest later to see how your own markers have moved.

Coming soon · The Welleo App connects your test results, supplement plan, and follow-up in one place.